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BCR/ABL(ABL1) Plus Translocation, Dual Fusion

Applications
hematology
Catalogue Numbers
LPH 038-A (100μl)

The BCR probe mix contains a probe, which extends 169kb centromeric to BCR and contains the genes GNAZ and RAB36. A second probe covers a 148kb region, which is positioned 261kb telomeric to BCR. Both are labeled in green. For ABL1 a probe contig covers 346kb from the middle of the FUBP3 gene to a point 64kb telomeric to ABL1 and it is labeled in red. There is an additional blue probe that covers a 173kb region and spans the whole ASS1 gene. The ASS1 probe is located 212kb from centromeric end of the ABL1 gene.

Probe Specification

  • ABL1, 9q34.11-q34.12, Red
  • BCR, 22q11.22-q11.23, Green
  • ASS1, 9q34.11-q34.12, Blue
I first came across Cytocell FISH probes in a previous lab I worked in and I was struck by the quality of the products. Since this time, I have been recommending and introducing Cytocell probes across all application areas — now they are the primary FISH probes used in our lab. They have an excellent range of products and their ready-to-use reagent format saves considerable time. As a matter of fact, at a recent conference there was a discussion about the lack of commercial probes for a particular disorder and I was happy to point the participants in the direction of the Cytocell catalogue, which contains the exact probes required. Elizabeth Benner, Medical Technologist at the University of Arizona Health Network

Microscope Images

BCR ABL plus translocation magnified

Disclaimer

Analyte Specific Reagent.
Analytical and performance characteristics are not established.